Hung T. Nguyen
Head of BioSim Lab
nguyenh [at] buffalo.edu
tienhung_91
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Department of Chemistry
471 Natural Sciences Complex
Buffalo, NY 14260
Short Bio
I got my PhD from Rutgers University in BioMaPS Institute (now the Center for Quantitative Biology), under the supervision of Prof. David A. Case. My doctoral dissertation focused on understanding the interactions between solvent and proteins & nucleic acids, and characterizing the spatial distribution of solvent around biomolecules using computational modeling and liquid state theory. This work had been done in collaboration with the group of Prof. Lois Pollack.
I then joined the group of Prof. Dave Thirumalai as a postdoc. There I initially worked on RNA folding, in particular the effects of ions on RNA folding thermodynamics. Later, I switched gear to develop computational models to understand the phase separation behaviors of RNA, as well as the conformational heterogeneity and dynamics of intrinsically disordered proteins (IDPs).
I joined the Department of Chemistry at the University at Buffalo as an Assistant Professor in August 2023. Check out our current interests.
Curriculum Vitae
General Information
| Full Name | Hung T. Nguyen |
| Position | Assistant Professor, Department of Chemistry, University at Buffalo |
| Languages | English, Vietnamese |
| Research interests | Computational modeling of biomolecular systems |
Education
- 2016
Ph.D.
Rutgers University, NJ
- Computational Biology & Molecular Biophysics
- 2008
BS
University of Science, Vietnam National University Ho Chi Minh City, Vietnam
- Physical Chemistry
Experience
- 2023 - now
Assistant Professor of Chemistry
Department of Chemistry, University at Buffalo, NY
- 2016 - 2023
Postdoctoral Fellow
Department of Chemistry, University of Texas - Austin, TX
- Mentor - Prof. Dave Thirumalai
- 2010 - 2016
Graduate Student
BioMaPS Institute, Rutgers University, NJ
- Advisor - Prof. David A. Case
- 2008 - 2010
Research Fellow
Institute for Computational Science and Technology, HCM City, Vietnam
- 2009
Visiting Research Fellow
Nagoya University, Nagoya, Japan
Presentations
- Aug 2023
Genome, Environment and Microbiome (GEM) Community of Excellence, UB (invited)
- Structure and dynamics of RNA in biomolecular condensate
- Feb 2023
Department of Biochemistry and Molecular Biophysics, Kansas State (invited)
- Disease-associated condensate formation under a computational lens
- Feb 2023
Biophysical Society Meeting, San Diego CA
- Structure and dynamics of RNA in biomolecular condensate
- Aug 2022
33rd IUPAP Conference on Computational Physics, virtual
- Condensates in RNA repeat sequences are heterogeneously organized and exhibit reptation dynamics
- Feb 2021
Biophysical Society Meeting, virtual
- Liquid–liquid phase separation of repeat disorder sequences leads to RNA conformational and dynamical heterogeneity
- Apr 2019
American Chemical Society National Meeting, Orlando FL
- Free energy changes in the folding transitions of RNA driven by divalent cations
- Feb 2018
Biophysical Society Meeting, San Francisco CA
- Calculation of ion-dependent RNA folding free energy using coarse-grained simulation
- Oct 2015
National Renewable Energy Laboratory, Golden CO
- Water–biomolecule interaction studied by 3D-RISM and X-ray scattering
- Mar 2015
American Chemical Society National Meeting, Denver CO
- Water–biomolecule interaction studied by 3D-RISM and X-ray scattering
- Feb 2013
Institute for Computational Science and Technology, Vietnam (invited)
- Classical molecular dynamics simulation with AMBER
- Feb 2010
International Workshop on Computational Biophysics, Vietnam
- Top-hits for Swine Flu Neuraminidase identified by virtual screening using ensemble-based docking